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KMID : 0359920080270060733
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Korean Journal of Nephrology
2008 Volume.27 No. 6 p.733 ~ p.737
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Concurrent IgA Nephropathy and Minimal Change Disease in a Patient with Polycythemia Vera: A Case Report
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Jung Young-Jong
Kim Beom
Cho Yong-Mee
Kim Hee-Sup
Kim Ji-Ho
Kim Soo-Yeun
Kim Bong-Seog
Choi Youn-Mi
Moon Kyoung-Hyoub
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Abstract
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Polycythemia vera is a hematopoietic stem cell disease, characterized by sustained and excessive proliferation of erythrocytic, granurocytic and megakaryocytic cells in the bone marrow resulting in pancytosis in peripheral blood. There have been a few reports of glomerulonephritis with polycythemia vera, most of which were IgA nephropathy. We report a case of a polycythemia vera associated with proteinuria. We confirmed the polycythemia vera according to World Health Organization criteria. Renal pathology showed IgA nephropathy and minimal change disease. Periodic phlebotomy was done and hydroxyurea was administered without specific managements for renal disease. After 3-month treatment,
hemoglobin level decreased and proteinurea disappeared.
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KEYWORD
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Polycythemia vera, IgA nephropathy, Minimal change glomerulopathy
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